Angiofox 25 mg (30 Tablets) Active Ingredient: Captopril 25 mg – Angiotensin-Converting Enzyme (ACE) Inhibitor Therapeutic Class:Antihypertensive and heart failure medication (ACE inhibitor) Indications: Hypertension (high blood pressure) Congestive heart failure (alone or in combination with diuretics/digitalis) Post-myocardial infarction (to improve survival and heart function) Diabetic nephropathy (especially in type 1 diabetes to protect kidneys) Dosage: Hypertension: Usually 25–50 mg 2–3 times daily Heart failure: Start with 6.25–12.5 mg 2–3 times daily, gradually increased under medical supervision Should be taken 1 hour before meals (food reduces absorption) Dose adjustments required in renal impairment or elderly patients Mechanism of Action: Inhibits angiotensin-converting enzyme, reducing formation of angiotensin II Causes vasodilation, lowers blood pressure, and decreases cardiac workload Reduces aldosterone secretion, leading to less sodium and water retention Precautions: Contraindicated in: History of angioedema with ACE inhibitors Pregnancy, especially 2nd and 3rd trimesters Severe renal impairment or bilateral renal artery stenosis Use with caution in: Patients with kidney or liver disorders Diabetic patients (risk of hypoglycemia) Those taking potassium supplements or potassium-sparing diuretics (risk of hyperkalemia) Monitor blood pressure, renal function, and serum potassium regularly Possible Side Effects: Dry, persistent cough (common) Dizziness or postural hypotension Fatigue or weakness High potassium (hyperkalemia) Loss of taste (dysgeusia) Rare: Angioedema, rash, or renal dysfunction Storage: Store below 25°C in a cool, dry place away from moisture and sunlight Keep out of reach of children
